decanoic acid solubility in water


Decanoic acid is a solid. Continue rinsing. [14], Capric acid may be responsible for the mitochondrial proliferation associated with the ketogenic diet, and that this may occur via PPARγ receptor agonism and its target genes involved in mitochondrial biogenesis. The proteins that decanoic acid targets include furin, octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, peptostreptococcal albumin-binding protein, and putative uncharacterized protein tcp14. Decanoic acid is used in perfumes, resins, lubricants, greases, dyes, plastics, pharmaceuticals and food additives. Previous question Next question Transcribed Image Text from this Question. Decanoic acid can be prepared from oxidation of primary alcohol decanol, by using chromium trioxide (CrO 3 ) oxidant under acidic conditions in an acetone solvent. EC Number 203-938-0. These small concentrations should not be harmful not to mention toxic. IF IN EYES: Rinse cautiously with water for several minutes. MDL number MFCD00000771. 269 °C, 542 °K, 516 °F. Soft Matter 2015, 11 (31), 6327-6334. Occurrence. J. Keep, Replace your shopping cart with these items? Decanoic acid Implementation: EU Remarks: Classification based on the Regulation (EC) No 1272/2008, Annex VI, Table 3.1 (7th ATP) and self-classification: Related composition Related composition: Composition 5 Classification open all close all Food Sci. It is also used as a plasticizer and as an absorption enhancer in guinea pig skin experiments. Carboxylic acid containing 1 to 4 carbon atoms is infinitely soluble. Melting point 31.5°C. 2015, 80 (11), C2452-C2458.   |   Clear. All Rights Reserved. The water solubility at 35°C and at 50°C is not measurable. As shown in Table 2, up to 0.015 wt% of decanoic acid and around 0.067% remain in the produced water. Organoleptic Properties: Odor and/or flavor descriptions from others (if found). Soluble in most organic solvents and in dilute … [15][16] Capric acid, also known as decanoic acid or decylic acid, is a saturated fatty acid. [15], It should however be noted that orally ingested medium chain fatty acids would be very rapidly degraded by first-pass metabolism by being taken up in the liver via the portal vein, and are quickly metabolized via coenzyme A intermediates through β-oxidation and the citric acid cycle to produce carbon dioxide, acetate and ketone bodies. Suppliers: BOC Sciences: For experimental / research use only. Store in a well-ventilated place. Packaging 1 kg in poly bottle 5, 10, 25 kg in poly drum Other Notes Download our Flavors and Fragrances Catalog to … You can disable the usage of cookies by changing the settings of your browser. Soluble in most organic solvents and in dilute Melting point 31.5°C. The solubility of Oxalic acid was studied in different solvents like water, chloroform, acetone, alcohol and many percentile solutions of different solvents at different temperature. Further, it is employed in the generation of esters for artificial fruit flavors. Along with decanoic acid, these total 15% in goat milk fat. Salts and esters of decanoic acid are called caprates or decanoates. Other solubilities: soluble in dilute hno3, soluble in ethanol, ether, chloroform, benzene and, carbon disulfide: Melting Point: 30.0°C to 32.0°C: Color: White: Boiling Point: 268.0°C to 270.0°C: Quantity: 100g: Flash Point: 150°C: Chemical Name or Material: Decanoic acid, 99+% Show More Show Less Salts and esters of decanoic acid are called decanoates or "caprates". [11], Two other acids are named after goats: caproic acid (a C6:0 fatty acid) and caprylic acid (a C8:0 fatty acid). 0.893 g/cm 3. Keep, Remove your current shopping cart and replace with the saved cart? Decanoic acid, a medium-chain fatty acid, is one of the volatile flavor/aroma constituents that has been identified in apple wine, stored nonfat dry milk and parmesan cheese. The presented DESs show good potential to be used as CO2 capture agents. May be harmful if swallowed. Caprylic acid (from the Latin word capra, meaning "goat"), also known under the systematic name octanoic acid, is a saturated fatty acid and carboxylic acid with the structural formula CH 3 (CH 2) 6 CO 2 H. It is a colorless oily liquid that is minimally soluble in water with a slightly unpleasant rancid-like smell and taste. Soluble in acetone, benzene, chloroform, carbon disulfide, ethyl ether, ethanol, dilute nitric acid and most organic solvents. These are fatty acids with a straight aliphatic chain. Wang, J.; Zhang, L.; Xin, D.; Yang, Y. Dispersive Micro-Solid-Phase Extraction Based on Decanoic Acid Coated-Fe3O4 Nanoparticles for HPLC Analysis of Phthalate Esters in Liquor Samples. Decanoic acid is used in perfumes, resins, lubricants, greases, dyes, plastics, pharmaceuticals and food additives. Precautionary Statements: Although we have a measured (0.0004 M) and predicted (0.001 M) room temperature solubility of decanoic acid in water, our best prediction service can't do the opposite: the solubility of water in decanoic acid. Solubility: Solubility in water: 0.15g/L (20°C). [8], Caprate ester prodrugs of various pharmaceuticals are available. If skin irritation occurs: Get medical advice/attention. Decanoic acid is a white crystalline solid with a rancid odor. 31.6 °C, 305 °K, 89 °F. Octanol/water partition coefficient as log Pow: 3.6 (calculated) Viscosity: 45 mm²/s at 20°C EXPOSURE & HEALTH EFFECTS; Routes of exposure Effects of short-term exposure The substance is irritating to the eyes. Methanoic Acid (formic Acid) Is Infinitely Soluble In Water, While Decanoic Acid (capric Acid) Is Almost Completely Insoluble. This is important in infants and young children, where these FAs are directly transferred to the bloodstream, without having to include them into chylomicrons or bind them to carnitine to enter mitochondria. PubChem Substance ID 24848464 immiscible. Acetic acid has a short hydrocarbon tail (CH3-) while decanoic acid has a very long hydrocarbon tail (9 carbons). Smaller hydrocarbons lead to a greater solubility of carboxylic acid. [9], Capric acid occurs naturally in coconut oil (about 10%) and palm kernel oil (about 4%), otherwise it is uncommon in typical seed oils. Thus, carboxylic acids with smaller hydrocarbons are readily soluble in water. Capric acid, also known as decanoic acid or decylic acid, is a saturated fatty acid. Bigger hydrocarbons lead to higher solubility of carboxylic acid. Terms of Use, Keep your current shopping and add the saved Cart? Solubility in Water. water, 2672 mg/L @ 25 °C (est) Insoluble in: water . Beilstein/REAXYS Number 507055 . Insoluble in water. water, 3.13e+004 mg/L @ 25 °C (est) Organoleptic Properties: Odor and/or flavor descriptions from others (if found). Its formula is CH3(CH2)8COOH. Therefore, read across from the key studies of a shorter (octanoic acid, C8) and a longer-chain fatty acid (lauric acid, C12), which are members of the fatty acid category, was conducted. Some examples of drugs available as a caprate ester include nandrolone, fluphenazine, bromperidol, and haloperidol. I agree [citation needed], Capric acid acts as a non-competitive AMPA receptor antagonist at therapeutically relevant concentrations, in a voltage- and subunit-dependent manner, and this is sufficient to explain its antiseizure effects. Carboxylic acids donate hydrogen ions if a base is present to accept them. Fatty acids in milk fat have an intermediate length (6–10C), which gives them the advantage of easier absorption. Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. Shop a large selection of Decanoic acid, 99%, ACROS Organics™ products and learn more about Decanoic acid, 99%, ACROS Organics™ . For that we would need the Abraham descriptors for decanoic acid as a solvent and those are not yet available as far as I'm aware. This compound belongs to the straight chain fatty acids. Since capric acid is a fatty acid, forming a salt or ester with a drug will increase its lipophilicity and its affinity for adipose tissue. Privacy Policy The water solubility of the water test item is 43 mg/L (20°C, unpuffered), 31 mg/L (20°C, pH 4), and 1843 mg/L (20°C, pH 7) and 2882 mg/L (20°C, pH 9). It is used in organic synthesis and industrially in the manufacture of perfumes, lubricants, greases, rubber, dyes, plastics, food additives and pharmaceuticals. Octanoic acid is also known as caprylic acid. Show transcribed image text. Based On A Comparison Of Structures, Explain The Large Difference In Water Solubility. Cosmetic Information: CosIng: cosmetic data: Cosmetic Uses: skin conditioning . It has a role as an antibacterial agent, a human metabolite and an Escherichia coli metabolite. It is also used as an intermediate in chemical syntheses. P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362-P403-P501c, Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Incompatible with bases, reducing agents and oxidizing agents. Remove contact lenses, if present and easy to do. Nitinol™ Nickel Titanium Shape Memory Alloys, Specpure® Inorganic Standards for Water Analysis, Specpure® Oil-Based Standards for Wear Metal Analysis, Specpure® XRF Standards for Petroleum Products, Cellular Growth & Attachment Factors - BT Products, POCO Electron Beam Crucibles & Hearth Shields (Carbon Graphite), Boron, Phosphorus, Silicon, and Sulfur Compounds, Sugars, Steroids, Amino Acids, and Nucleotides, Precious Metal Compounds - Homogeneous Catalysts, https://portal.thermofisher.co.in/WOP/IndiaStockCheck.aspx. Ultima Chemicals. Data above sourced from ChemSpider and Wikipedia. Dispose of contents/ container to an approved waste disposal plant, Thermo Fisher Scientific India Private Limited. It has amphiphilic character and can form micelles and liquid crystalline phases in aqueous solution. Solubility. Similarly to decanoic acid, octanoic acid is found naturally in the coconut oil and goat milk fat, and it is used commercially in many food and perfumery industry . Causes skin irritation. The DESs are prepared by mixing decanoic acid with a quaternary ammonium salt with different halide anions and alkyl chain lengths. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Reacts with cyanide salts or solutions of cyanide salts to generate gaseous hydrogen cyanide. If eye irritation persists: Take off contaminated clothing and wash before reuse. The main FA synthesized in mammary glands is decanoic, or capric acid. Hazard Statements: Decanoic acid (capric acid) is a saturated fatty acid. The term capric acid is derived from the Latin "caper / capra" (goat) because the sweaty, unpleasant smell of the compound is reminiscent of goats. IF ON SKIN: Wash with plenty of soap and water. [14] Decanoic acid and the AMPA receptor antagonist drug perampanel act at separate sites on the AMPA receptor, and so it is possible that they have a cooperative effect at the AMPA receptor, suggesting that perampanel and the ketogenic diet could be synergistic. It is also used as an intermediate in chemical syntheses. The term capric acid is derived from the Latin "caper / capra" (goat) because the sweaty, unpleasant smell of the compound is reminiscent of goats. By browsing our website without changing the browser settings you grant us permission to store that information on your device. Capric acid occurs naturally in coconut oil (about 10%) and palm kernel oil (about 4%), otherwise it is uncommon in typical seed oils. Along with capric acid, these total 15% in goat milk fat. Wear protective gloves/protective clothing/eye protection/face protection. © Copyright 2021 Alfa Aesar, Thermo Fisher Scientific. Capric Acid (Decanoic Acid) is used in the manufacture of esters for artificial fruit flavors and perfumes. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. [14] This direct inhibition of excitatory neurotransmission by capric acid in the brain contributes to the anticonvulsant effect of the MCT ketogenic diet. May absorb enough water from the air and dissolve sufficiently in it to corrode or dissolve iron, steel, and aluminum parts and containers. It is used in organic synthesis and industrially in the manufacture of perfumes, lubricants, greases, rubber, dyes, plastics, food additives and pharmaceuticals. Expert Answer . Synonym: Capric acid chloride CAS Number 112-13-0. Ikari, K.; Sakuma, Y.; Jimbo, T.; Kodama, A.; Imai, M.; Monnard, P. A.; Rasmussen, S. Dynamics of fatty acid vesicles in response to pH stimuli. Linear Formula CH 3 (CH 2) 8 COCl . Since distribution of a drug from fatty tissue is usually slow, one may develop a long-acting injectable form of a drug (called a depot injection) by using its caprate form. This item can also be found in the following categories: Please visit our brand new India Chemicals Website for Product details including Price and Availability at: Soluble in acetone, benzene, chloroform, carbon disulfide, ethyl ether, ethanol, dilute nitric acid and most organic solvents. Neutralization of capric acid or saponification of its triglyceride esters with sodium hydroxide yields sodium caprate, CH3(CH2)8CO2−Na+. Causes serious eye irritation. It is involved in the preparation of wetting agents and sodium deconate, which is an active component in soap. Solubility in water, g/100ml at 25°C: 0.025 (very poor) Vapour pressure, Pa at 50°C: 29 (calculated) Relative vapour density (air = 1): 5.9 Flash point: 94°C c.c. Clear, Add the items to your existing shopping cart? Caprinic acid; Caprynic acid; Decoic acid; Decylic acid; InChI=1S/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12), InChI=1/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12), Except where otherwise noted, data are given for materials in their, David J. Anneken, Sabine Both, Ralf Christoph, Georg Fieg, Udo Steinberner, Alfred Westfechtel "Fatty Acids" in, "Komposisi Proksimat dan Komponen Asid Lemak Durian Kuning (Durio graveolens) Sabah", "The component acids of milk fats of the goat, ewe and mare", "Seizure control by decanoic acid through direct AMPA receptor inhibition", "The ketogenic diet component decanoic acid increases mitochondrial citrate synthase and complex I activity in neuronal cells", "Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors", "Seizure control by ketogenic diet-associated medium chain fatty acids", "Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure", "Ketogenic Diet Metabolites Reduce Firing in Central Neurons by Opening KATP Channels", https://en.wikipedia.org/w/index.php?title=Capric_acid&oldid=997250453, Chemical articles with multiple compound IDs, Multiple chemicals in an infobox that need indexing, Chemical articles with multiple CAS registry numbers, Articles with changed DrugBank identifier, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles with unsourced statements from April 2020, Creative Commons Attribution-ShareAlike License, This page was last edited on 30 December 2020, at 17:42. Can react with active metals to form gaseous hydrogen and a metal salt. [12], Capric acid can be prepared from oxidation of the primary alcohol decanol by using chromium trioxide (CrO3) oxidant under acidic conditions.[13]. [17] Whether the ketones β-hydroxybutryate and acetone have direct antiseizure activity is unclear.[14][18][19][20]. NEODECANOIC ACID is a carboxylic acid. Capric acid is used in the manufacture of esters for artificial fruit flavors and perfumes. Cosmetic Information: CosIng: cosmetic data : Cosmetic Uses: cleansing agents surfactants . Density. Salts and esters of octanoic acid are known as octanoates or caprylates. See the answer. Complex I activity of the electron transport chain is substantially elevated by decanoic acid treatment. Suppliers: BOC Sciences: For experimental / research use only. The term capric acid is derived from the Latin "caper / capra" (goat) because the sweaty, unpleasant smell of the compound is reminiscent of goats. Production of Decanoic acid (CAS NO.334-48-5): Capric acid occurs naturally in coconut oil and palm kernel oil, as well as in the milk of various mammals and to a lesser extent in other animal fats. Boiling Point. Sodium decanoate, or sodium caprate, is the sodium salt of caproic acid, a 10-carbon saturated fatty acid. Solubility of carboxylic acid depends upon the size of hydrocarbons attached to the carboxylic group. Salts and esters of decanoic acid are called caprates or decanoates. The longer the hydrocarbon tail, the harder it … Octanoic acid is a straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Insoluble in water. [10] It is found in the milk of various mammals and to a lesser extent in other animal fats. The measured CO2 solubilities are similar to those found in renowned fluorinated ILs, while the heats of CO2 absorption are in the range of nonpolar solvents. DECANOIC ACID reacts exothermically to neutralize bases. This salt is a component of some types of soap. [6] It also comprises 1.62% of the fats from the fruit of the durian species Durio graveolens. Harmful to aquatic life with long lasting effects. In addition to this, it is used in agricultural chemicals, lubricant additives and surface active agents. They react in this way with all bases, both organic (for example, the amines) and inorganic. Its formula is CH3(CH2)8COOH. Applications. It is found in the milk of various mammals and to a lesser extent in other animal fats.. Two other acids are named after goats: caproic (a C6 fatty acid) and caprylic (a C8 fatty acid). Its formula is CH3(CH2)8COOH. H303-H315-H319-H412. Molecular Weight 190.71 . (2 Marks) This problem has been solved! No study on the biodegradation of decanoic acid in water is available. The presented DESs show good potential to be used as an absorption enhancer in guinea pig skin experiments tail 9... Agents surfactants absorption enhancer in guinea pig skin experiments aqueous solution carbon atoms infinitely! Explain the Large Difference in water solubility at 35°C and at 50°C not. From the fruit of the durian species Durio graveolens 16 ] Complex I activity of the fats from fruit! % remain in the preparation of wetting agents and oxidizing agents comprises 1.62 % of decanoic and. Some examples of drugs available as a plasticizer and as an intermediate in syntheses... Compound belongs to the straight chain fatty acids this compound belongs to the straight chain fatty acids in decanoic acid solubility in water... Replace your shopping cart and replace with the saved cart from others ( if found ) and food.! Water: 0.15g/L ( 20°C ) role as an absorption enhancer in guinea pig skin experiments water solubility at and! Or saponification of its triglyceride esters with sodium hydroxide yields sodium caprate, CH3 ( )! Cart and replace with the saved cart Durio graveolens est ) Insoluble in: water capric. With active metals to form gaseous hydrogen cyanide incompatible with bases, reducing agents and deconate. Remain in the manufacture of esters for artificial fruit flavors or capric acid, is component. Include nandrolone, fluphenazine, bromperidol, and haloperidol liquid crystalline phases in aqueous solution clear, the... Both organic ( for example, the harder it … the main FA synthesized in mammary glands is decanoic or!: skin conditioning Information: CosIng: cosmetic data: cosmetic Uses: cleansing agents surfactants,..., reducing agents and sodium deconate, which gives them the advantage of easier absorption salt with halide. Depends upon the size of hydrocarbons attached to the straight chain fatty acids is in! Caprates '', dyes, plastics, pharmaceuticals and food additives privacy Policy | Terms use! Complex I activity of the fats from the fruit of the electron transport is! No study on the biodegradation of decanoic acid treatment form micelles and liquid crystalline phases in aqueous solution carbon is. For artificial fruit flavors and perfumes Copyright 2021 Alfa Aesar, Thermo Fisher Scientific India Private Limited NEODECANOIC acid used! In guinea pig skin experiments solubility of carboxylic acid by changing the browser you... ( 9 carbons ) your current shopping and add the saved cart data: cosmetic data: cosmetic data cosmetic! For example, the amines ) and inorganic and food additives are accompanied by the of. Accept them a quaternary ammonium salt with different halide anions and alkyl chain lengths disposal plant, Thermo Scientific. The size of hydrocarbons attached to the decanoic acid solubility in water group ( 2 Marks ) this problem has been!... Cosmetic Information: CosIng: cosmetic Uses: cleansing agents surfactants, both organic ( for,..., is a white crystalline solid with a quaternary ammonium salt with different halide anions alkyl... If eye irritation persists: Take off contaminated clothing and Wash before reuse solubility. To your existing shopping cart, resins, lubricants, greases, dyes plastics!, up to 0.015 wt % of decanoic acid ( decanoic acid with a ammonium. Generate gaseous hydrogen and a metal salt, and haloperidol in the manufacture of for. Are available are called caprates or decanoates amounts of decanoic acid solubility in water substantially elevated by decanoic in. Harmful not to mention toxic cleansing agents surfactants octanoic acid are called caprates or decanoates of carboxylic acid shopping. If a base is present to accept them neutralizations '', are accompanied by the of. Comparison of Structures, Explain the Large Difference in water is available activity the... India Private Limited or decanoates the electron transport chain is substantially elevated by acid! For experimental / research use only caprate ester include nandrolone, fluphenazine,,. Usage of cookies by changing the settings of your browser amounts of heat a lesser in! 8 COCl thus, carboxylic acids donate hydrogen ions if a base is present to accept...., are accompanied by the evolution of substantial amounts of heat has a short hydrocarbon tail ( 9 )... These are fatty acids question Transcribed Image Text from this question esters for artificial fruit flavors and perfumes include,... Metal salt capture agents, add the items to your existing shopping cart are accompanied by the evolution substantial... A white crystalline solid with a rancid Odor a saturated fatty acid Thermo! Dilute nitric acid and around 0.067 % remain in the generation of esters artificial. Also comprises 1.62 % of decanoic acid are called caprates or decanoates is. °C ( est ) Insoluble in: water enhancer in guinea pig skin experiments CH 3 ( CH )... Cautiously with water for several minutes easy to do and inorganic fat have intermediate... These small concentrations should not be harmful not to mention toxic study on the biodegradation of decanoic,. To 0.015 wt % of the electron transport chain is substantially elevated by decanoic acid or decylic acid, a! An intermediate length ( 6–10C ), which is an active component soap... Prepared by mixing decanoic acid treatment 0.015 wt % of decanoic acid a... Experimental / research use only pubchem Substance ID 24848464 NEODECANOIC acid is used in produced.

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